File Name: biochemistry and molecular biology of antimicrobial drug action .zip
Reviewed: February 14th Published: February 27th Pathogenic microorganisms can infect tissues of human by destroying cellular functions. Microorganisms themselves or their toxins can damage host cells. Microbial infections are treated with antimicrobials by either inhibiting the microbial growth or killing the microorganism. Antibiotics are widely being used not only in the treatment of acute and chronic infections, but also in the prophylactic treatment [ 1 ]. Targets of antimicrobials are cell membrane, cell wall, protein synthesis, nucleic acid synthesis, and biological metabolic compound synthesis Figure 1 [ 2 ].
Antibacterial agents are a group of materials that selectively destroy bacteria by interfering with bacterial growth or survival. With the emergence of resistance phenomenon of bacterial pathogens to current antibiotics, new drugs are frequently entering into the market along with the existing drugs, and the alternative compounds with antibacterial functions are being explored. Due to the advantages of their inherent biochemical and biophysical properties including precise targeting ability, biocompatibility, biodegradability, long blood circulation time, and low cytotoxicity, biomolecules such as peptides, carbohydrates, and nucleic acids have huge potential for the antimicrobial application and have been extensively studied in recent years. In this review, antimicrobial therapeutic agents composed of three kinds of functional biological molecules were summarized. In addition, the research progress of antibacterial mechanism, chemical modification, and nanoparticle coupling of those biomolecules were also discussed. Bacteria that cause bacterial infections and disease are called pathogenic bacteria. Antimicrobial therapeutic agents are a group of materials that fight against pathogenic bacteria by killing or reducing the metabolic activity of bacteria.
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections , and antibiotic medications are widely used in the treatment and prevention of such infections. A limited number of antibiotics also possess antiprotozoal activity. However, both classes have the same goal of killing or preventing the growth of microorganisms, and both are included in antimicrobial chemotherapy. Antibiotics have been used since ancient times. Many civilizations used topical application of mouldy bread, with many references to its beneficial effects arising from ancient Egypt, Nubia, China, Serbia, Greece, and Rome.
Once production of your article has started, you can track the status of your article via Track Your Accepted Article. Help expand a public dataset of research that support the SDGs. Journal of Molecular Biology JMB provides high quality, comprehensive and broad coverage in all areas of molecular biology. The journal publishes original scientific research papers that provide mechanistic and functional insights and report a significant advance to the field. The journal encourages The journal encourages the submission of multidisciplinary studies that use complementary experimental and computational approaches to address challenging biological questions. Since , JMB is ensuring some basic principles in the services it provides to all authors:.
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Bacteria that cause bacterial infections and disease are called pathogenic bacteria. They cause diseases and infections when they get into the body and begin to reproduce and crowd out healthy bacteria or to grow into tissues that are normally sterile. To cure infectious diseases, researchers discovered antibacterial agents, which are considered to be the most promising chemotherapeutic agents.
It seems that you're in Germany. We have a dedicated site for Germany. Authors: Franklin , Trevor J. This stimulating new edition of the well-respected title Biochemistry and Molecular Biology of Antimicrobial Drug Action primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use which have been invaluable as research tools in biochemistry.
Skip to content. Skip to navigation. Different antibiotics have different modes of action, owing to the nature of their structure and degree of affinity to certain target sites within bacterial cells. Click here to download a print ready PDF of this module. East Lansing, MI
Once production of your article has started, you can track the status of your article via Track Your Accepted Article. Help expand a public dataset of research that support the SDGs. Part C: Toxicology and Pharmacology CBPC , focuses on toxicological mechanisms at different levels of organization, primarily chemical and drug action, biotransformation of xenobiotics Part C: Toxicology and Pharmacology CBPC , focuses on toxicological mechanisms at different levels of organization, primarily chemical and drug action, biotransformation of xenobiotics, endocrine disruptors, nanoparticles, pharmaceuticals, and natural products chemistry. Most studies employ a molecular approach in combination with observations of higher levels of organization to assess the mechanism by which xenobiotics affect physiology. Analytical verification of exposure concentrations is strongly recommended for manuscripts reporting toxicological studies. All four CBP journals support and follow the editorial direction from all the major societies in the field:.
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This stimulating new edition of the well-respected title Biochemistry and Molecular Biology of Antimicrobial Drug Action primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use which have been invaluable as research tools in biochemistry. Since the previous edition, of this book, the impact of molecular biology on our understanding of the mechanisms of antimicrobial action and drug resistance has evolved significantly. Completely updated and rewritten, Biochemistry and Molecular Biology of Antimicrobial Drug Action will be of great use to medical and biological sciences students taking courses in pharmacology, molecular biology, microbiology, biochemistry and chemotherapeutics. Because of the wealth of information within the covers of this important book, all those involved in research into drug action and development, whether in the pharmaceutical industry or academia, will find Biochemistry and Molecular Biology of Antimicrobial Drug Action invaluable. It should also be on the shelves of all libraries, in university medical schools and departments of biological sciences, biochemistry and pharmacology.
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